Springer Seminars in Immunopathology

, Volume 21, Issue 2, pp 191–197 | Cite as

Gene therapy in the treatment of ocular inflammation

  • Karl Csaky
  • Robert Nussenblatt


Gene therapy may become a powerful therapeutic modality in the treatment of both ocular inflammatory disease and as a means of preventing rejection following tissue transplantation. By directly introducing into ocular cells genes that encode proteins capable of down-regulating the immune response, gene therapy has potential for both therapy and as a method for studying mechanisms of disease. While marked and rapid advances in the study of gene therapy have been realized, technical questions regarding the appropriate vector or the choice of efficacious immunomodulatory protein still remain.


Immune Response Internal Medicine Gene Therapy Inflammatory Disease Cell Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1999

Authors and Affiliations

  • Karl Csaky
    • 1
  • Robert Nussenblatt
    • 1
  1. 1.National Eye InstituteBethesdaUSA

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