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Synthesis and transformations of some pyrido[2,3-d]pyrimidines

Synthesen und Umwandlungen einiger Pyrido[2,3-d]pyrimidine

  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

A new synthetic approach for pyrido[2,3-d]pyrimidine 3-oxides and other pyrido[2,3-d]pyrimidines has been developed. This bicyclic system readily undergoes ring opening to give a variety of products, depending on the reagent and reaction conditions.

Zusammenfassung

Synthesen von Pyrido[2,3-d]pyrimidin-3-oxiden und einigen anderen Pyrido[2,3-d]pyrimidinen werden beschrieben. Das bicyclische System reagiert leicht unter Ringöffnung, wobei entsprechend den Reaktionsbedingungen und Reagenzien verschiedene Produkte entstehen.

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References

  1. Irwin WJ, Wibberley DG (1969) Adv Heterocycl Chem 10: 149

    Google Scholar 

  2. Mulvey DM, Cottis SG, Tieckelmann H (1964) J Org Chem 29: 2903

    Google Scholar 

  3. Osselaere JB, Lapiere CL (1974) Eur J Med Chem Chim Ther 9: 305

    Google Scholar 

  4. Shepherd RG, Fedrick JL (1965) Adv Heterocycl Chem 4: 145

    Google Scholar 

  5. Albert A,Howell CF (1962) J Chem Soc: 1591

  6. Albert A,McCormack JJ (1966) J Chem Soc C: 1117

  7. Albert A,McCormack JJ (1968) J Chem Soc C: 63

  8. Hayashi E, Higashino T (1964) Chem Pharm Bull 12: 1111

    Google Scholar 

  9. Hayashi E, Higashino T (1965) Chem Pharm Bull 13: 291

    Google Scholar 

  10. Higashino T, Suzuki K, Hayashi E (1978) Chem Pharm Bull 26: 3485

    Google Scholar 

  11. Albert A (1963) In: Physical methods in heterocyclic chemistry, vol 1, 1. Academic Press, New York

    Google Scholar 

  12. Wheatley PJ (1972) X-ray bond angles and lengths, physical methods. In: Handbook of molecular dimensions. Academic Press, New York (Physical methods in heterocyclic chemistry, vol. 5)

    Google Scholar 

  13. Dewar MJS, Thiel W (1977) J Am Chem Soc 99: 4899

    Google Scholar 

  14. Dewar MJS, Thiel W (1977) J Am Chem Soc 99: 4907

    Google Scholar 

  15. Kočevar M, Stanovnik B, Tišler M (1983) Tetrahedron 38: 823

    Google Scholar 

  16. Petrič A, Tišler M, Stanovnik B (1985) Monatsh Chem 116: 1309

    Google Scholar 

  17. Petrič A, Stanovnik B, Tišler M (1983) J Org Chem 48: 4132

    Google Scholar 

  18. Korbonits D,Kanzel-Szvoboda I,Horvath K (1982) J Chem Soc Perkin I: 759

  19. Ried W, Valentin J (1967) Liebigs Ann Chem 707: 250

    Google Scholar 

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Kočevar, M., Koller, J., Stanovnik, B. et al. Synthesis and transformations of some pyrido[2,3-d]pyrimidines. Monatsh Chem 118, 399–407 (1987). https://doi.org/10.1007/BF00809951

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  • DOI: https://doi.org/10.1007/BF00809951

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