Summary
The development of a facile and efficient method for the synthesis of 2,5-diaryl-s-triazolo[3,4-b]-1,3,4-thiadiazoles4 a–e from the corresponding 3-aryl-4-amino-5-mercapto-s-triazole (2), is described. 3-Aryl-4-arylideneamino-5-mercapto-s-triazoles (3 a–e) were cyclized to compounds4 a–e by heating in nitrobenzene for a few minutes.
Zusammenfassung
Es wird eine einfache und effiziente Synthese von 2,5-Diaryl-1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazolen (4 a–e) aus den entsprechenden 3-Aryl-4-amino-5-mercapto-1,2,4-triazolen (2) beschrieben. Die 3-Aryl-4-arylidenamino-5-mercapto-1,2,4-triazole (3 a–e) wurden mittels Erhitzen in Nitrobenzol zu den Verbindungen4 a–e cyclisiert.
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Part II: See Ref. [11]
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El-Emam, A.A., Moustafa, M.A., El-Subbagh, H.I. et al. Triazoles and fused triazoles, III: Facile and efficient synthesis of 2,5-disubstituted-s-triazolo[3,4-b]-1,3,4-thiadiazoles. Monatsh Chem 121, 221–225 (1990). https://doi.org/10.1007/BF00809535
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DOI: https://doi.org/10.1007/BF00809535