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UV-VIS and CD-spectroscopic investigations of intermolecular interactions of bile pigments with small proteins

UV-VIS und CD-spektroskopische Untersuchungen intermolekularer Wechselwirkungen von Gallenpigmenten mit kleinen Proteinen

  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary

The intermolecular complex formation of bilirubin and biliverdin with two proteins (basic pancreatic trypsin inhibitor and lysozyme) were studied by optical and chiroptical methods. Evidence for specific intermolecular interactions of biliverdin with both proteins was found. Bilirubin forms a soluble complex only with lysozyme.

Zusammenfassung

Die intermolekulare Komplexbildung von Bilirubin und Biliverdin mit zwei Proteinen (basischer pankreatischer Trypsininhibitor und Lysozym) wurden mittels optischer und chiroptischer Spektroskopie untersucht. Für Biliverdin konnten intermolekulare Wechselwirkungen mit beiden Proteinen nachgewiesen werden. Bilirubin bildet nur mit Lysozym einen löslichen Komplex.

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Marko, H., Müller, N. & Falk, H. UV-VIS and CD-spectroscopic investigations of intermolecular interactions of bile pigments with small proteins. Monatsh Chem 120, 163–168 (1989). https://doi.org/10.1007/BF00808759

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  • DOI: https://doi.org/10.1007/BF00808759

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