Abstract
Interferon is considered to participate in the formation and materialization of the immune response, and any antigenic determinant may be an interferonogen. To confirm the role of interferon in the formation of immunologic reactivity experimentally, an attempt was made to block the action of interferon by means of an anti-interferon serum. Injection of the anti-interferon serum into C57BL/6 mice immunized with L cells reduced the cytotoxic action of the lymphocytes and sera of these mice on target cells.
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Skurkovich, S.V., Klinova, É.G., Eremkina, E.I. et al. Immunodepressant action of anti-interferon serum. Bull Exp Biol Med 78, 1389–1391 (1974). https://doi.org/10.1007/BF00808713
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DOI: https://doi.org/10.1007/BF00808713