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α-Adrenergic structures of the intracranial vessels and their role in regulation of the cerebral circulation

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Radioiosotopic, electromagnetic, and resistographic investigations showed that division and stimulation of the cervical sympathetic nerves leads to considerable changes in the cerebral blood supply. The absence of fluctuations in the pH of the CSF during electrical stimulation of the sympathetic nerves suggests that spasm of the intracranial arteries is unconnected with changes in metabolism but is brought about by direct excitation of adrenergic structures of the intracranial vessels by mediator. Pharmacological analysis with the aid ofα- andβ-adrenoblocking drugs showed that the constrictor response of the cerebral vessels is due to excitation ofα-adrenergic structures.

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Authors
  1. R. S. Mirzoyan
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Mirzoyan, R.S. α-Adrenergic structures of the intracranial vessels and their role in regulation of the cerebral circulation. Bull Exp Biol Med 78, 1382–1385 (1974). https://doi.org/10.1007/BF00808711

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  • DOI: https://doi.org/10.1007/BF00808711

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