Abstract
Hydrocortisone and cocarboxylase injected into newborn rats increased their chances of survival after asphyxia. Asphyxia was accompanied by increased succinate and dihydroorotate dehydrogenase activity in the lymphocytes, by lymphocytosis, and by an increase in the number of monocytes with hyperbasophilia of their cytoplasm in the blood and tissues. Hydrocortisone and cocarboxylase had a normalizing effect on these changes.
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Literature Cited
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H. Czitober, M. Gollerkeri, and W. Dameshek, in: Proceedings of the 8th Congress of the European Society of Haematology, New York (1962).
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Dauranov, I.G. Metabolic changes in the lymphocytes of newborn rats in asphyxia. Bull Exp Biol Med 78, 1363–1364 (1974). https://doi.org/10.1007/BF00808705
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DOI: https://doi.org/10.1007/BF00808705