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Response of the thyroid gland to changes in the blood plasmin concentration

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In experiments on rabbits, plasmin (fibrinolysin), in a dose of 2000 units/kg modified the hormone-excreting function of the thyroid gland: 5 min after injection of the preparation the blood protein-bound iodine level was lowered, but 1 h after injection it was raised. In rabbits with depressed thyroid function fibrinolysin also inhibited the hormone-excretory function of the gland. If plasmin activity was reduced by ε-aminocaproic acid, the protein-bound iodine level rose. Heated fibrinolysin did not affect thyroid function.

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Authors
  1. V. F. Kirichuk
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Kirichuk, V.F. Response of the thyroid gland to changes in the blood plasmin concentration. Bull Exp Biol Med 78, 1356–1357 (1974). https://doi.org/10.1007/BF00808702

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  • DOI: https://doi.org/10.1007/BF00808702

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