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Synthesis of new pyridazino[4′,3′:4,5]-thieno[3,2-d]-1,2,3-triazine and pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazine derivatives

Synthese neuer Pyridazino[4′,3′:4,5]thieno[3,2-d]-1,2,3-triazin-und Pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazin-Derivate

  • Organische Chemie Und Biochemie
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Summary

8,9-Diphenylpyridazino[4′,3′:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-one (2), 3-substituted 8,9-diphenylpyridazino[4′,3′:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-ones (3a–c), 3,4-diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazin-8(7H)-one (4), 8-chloro-3,4-diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazine (5), 8-substituted 3,4-diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazines (6a–h) and 7-substituted 3,4-diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazin-8(7H)-ones(7a–c) were synthesized from 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carboxamide (1).

Zusammenfassung

Folgende Verbindungen wurden ausgehend von 5-Amino-3,4-diphenylthieno[2,3-c]pyridazin-6-carboxamid (1) synthetisiert: 8,9-Diphenylpyridazino[4′,3′:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-on (2), 3-substituierte 8,9-Diphenylpyridazino[4′,3′:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-one (3a–c), 3,4-Diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazin-8[7H]-on (4), 8-Chlor-3,4-diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazin (5), 8-substituierte 3,4-Diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazine (6a–h) und 7-substituierte 3,4-Diphenylpyrimido[4′,5′:4,5]thieno[2,3-c]pyridazin-8(7H)-one (7a–c).

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Authors and Affiliations

  1. Departamento de Química Fundamental e Industrial, Facultad de Ciencias, Universidad de La Coruña, E-15071, La Coruña, Spain

    J. M. Quintela, M. C. Veiga, R. Alvarez-Sarandés, L. González & C. Peinador

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  1. J. M. Quintela
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  2. M. C. Veiga
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  3. R. Alvarez-Sarandés
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  4. L. González
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  5. C. Peinador
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Quintela, J.M., Veiga, M.C., Alvarez-Sarandés, R. et al. Synthesis of new pyridazino[4′,3′:4,5]-thieno[3,2-d]-1,2,3-triazine and pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazine derivatives. Monatsh Chem 127, 1037–1043 (1996). https://doi.org/10.1007/BF00807576

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  • DOI: https://doi.org/10.1007/BF00807576

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