Summary
In order to get better insight into the structural reasons for different properties of copper(II) complexes withL-threonine,L-allo-threonine,L-N,N-dimethyl-threonine, andL-N,N-dimethyl-allo-threonine, their EPR spectra were studied as a function ofpH and temperature. AtpD∼9.4, in all complexes a change in the copper(II) coordination sphere from the “glycine” to the “hydroxy” type was observed. Inbis(L-threoninato)copper(II), the “hydroxy” type formed atpD∼9.4 was found to be stablized by increasing the temperature of the solution from 280 to 320 K. In all other copper(II) complexes, the conformational change is accompanied by the disruption of the Cu-N bond of one chelate ring.
Zuzammenfassung
Um einen besseren Einblick in die Beziehungen zwischen Struktur und Eigenschaften von Kupfer(II)-Komplexen mitL-Threonin,L-allo-Threonin,L-N,N-Dimethyl-Threonin undL-N,N-Dimethyl-allo-Threonin zu gewinnen, wurden ihre EPR-Spektren in Abhängigkeit vompH-Wert und von der Temperatur untersucht. Bei einempH-Wert von 9.4 (in deuterierter Lösung) wurde eine Veränderung in der Kupfer (II)-Koordinationssphäre festgestellt, die von einer „Glycin“-ähnlichen Konformation in eine vermutlich „Hydroxy“-ähnliche Konformation übergeht. Derbis(L-Threoninato)-Kupfer (II)-„Hydroxy“-Komplex wird durch eine Temperaturerhöhung von 280 auf 320K stabilisiert. Die Veränderung der Koordination vom „Glycin“-Typ wird von einem Bruch der Cu-N-Bindung eines Chelatrings begleitet.
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Noethig-Laslo, V., Paulić, N. Comparative EPR study of copper(II) complexes with threonine derivatives. Monatsh Chem 128, 1101–1108 (1997). https://doi.org/10.1007/BF00807560
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DOI: https://doi.org/10.1007/BF00807560