Abstract
A culture of the trophoblast was obtained from an early human embryonic chorion. Trophoblastic cells of four main types are described: giant, branched, fibroblastlike, and round. All the cells were rich in RNA and glycoproteins and had the complement of enzymes for the Krebs' pentose cycle, but had low succinate dehydrogenase activity. A marked cytotoxic effect of the lymphocytes of the healthy pregnant woman on allogeneic cells of the trophoblast culture and no interaction between neonatal lymphocytes and these trophoblastic cells were found.
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Laboratory of Immunology, Department of Immunology, Institute of Clinical and Experimental Medicine, Siberian Branch, Academy of Medical Sciences of the USSR, Novosibirsk. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 4, pp. 467–470, April, 1977.
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Trunova, L.A., Kaznacheev, V.P., Ignatovich, N.V. et al. Study of trophoblast cell culturesin vitro . Bull Exp Biol Med 83, 552–555 (1977). https://doi.org/10.1007/BF00807504
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DOI: https://doi.org/10.1007/BF00807504