Bulletin of Experimental Biology and Medicine

, Volume 83, Issue 4, pp 473–476 | Cite as

Peroxidation of lipids and degeneration of photoreceptors in the retina of rats with avitaminosis E

  • V. E. Kagan
  • G. V. Barybina
  • K. N. Novikov
Pathological Physiology and General Pathology


The formation of peroxidation products of lipids (hydroperoxides, dialkyl peroxides, “intermolecular cross linkages”) is sharply intensified in the retina of rats with alimentary avitaminosis Ein vivo and degeneration of the photoreceptors (mainly the layer of outer segments of the rods) develops. The experimental results are discussed on the basis of views regarding the antioxidant mechanism of action of α-tocopherolin vivo.

Key Words

rat retina avitaminosis E peroxidation of lipids degeneration of photoreception layer of the retina 


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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • V. E. Kagan
  • G. V. Barybina
  • K. N. Novikov

There are no affiliations available

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