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Monatshefte für Chemie / Chemical Monthly

, Volume 128, Issue 2, pp 191–200 | Cite as

Synthetic studies towards (±)-aristeromycin and its 5′-homo-analogue

  • H. Kapeller
  • H. Baumgartner
  • H. Griengl
Organische Chemie Und Biochemie

Summary

A new synthetic pathway to the carbocyclic nucleoside analogues (±)-aristeromycin (15) and its 5′-homo-derivative (17) has been developed starting form norborn-5-en-2-one using nucleophilic substitution of a sulfonate ester group by the aglycone.

Keywords

Nucleoside, carbocyclic Aristeromycin 

Synthesestudien zu (±)-Aristeromycin und seinem 5′-homo-Analogon

Zusammenfassung

Ausgehend von Norborn-5-en-2-on wurden neue Synthesewege für (±)-Aristeromycin (15) und sein 5′-homo-Analogon (17) entwickelt, wobei die Einführung der Base durchSN2-Austausch einer Sulfonsäureestergruppe erfolgt.

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Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • H. Kapeller
    • 1
  • H. Baumgartner
    • 1
  • H. Griengl
    • 1
  1. 1.Institute of Organic ChemistryTechnical University GrazGrazAustria

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