Summary
Convenient syntheses of 3,4-diphenyl-8-oxo-6-substituted-5,6,7,8-tetrahydropyrimido[4′,5′:4,5]thieno[2,3-c]pyridazines (4a-g), 3,4-diphenyl-8-oxo-6-substituted-7,8-dihydropyrimido[4′,5′:4,5]thieno[2,3-c]pyridazines (5a-g), 8-chloro-3,4-diphenyl-6-substituted-pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazines (6a-g), and 3,4,6-triphenyl-8-substituted-pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazines (7a-f) from 4-cyano-5,6-diphenylpyridazine-3(2H)-thione (1)via 5-amino-3,4-diphenyl-thieno[2,3-c]pyridazine-6-carboxamide (3) are reported.
Zusammenfassung
Einfache Synthesen von 3,4-Diphenyl-8-oxo-6-substituierten-5,6,7,8-tetrahydropyrimido[4′,5′:4,5]thieno[2,3-c]pyridazinen (4a-g), 3,4-Diphenyl-8-oxo-6-substituierten-7,8-dihydropyrimido[4′,5′:4,5]thieno[2,3-c]pyridazinen (5a-g), 8-Chlor-3,4-diphenyl-6-substituierten Pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazinen (6a-g) und 3,4,6-Triphenyl-8-substituierten-pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazinen (7a-f) aus 4-Cyano-5,6-diphenylpyridazin-3(2H)-thion (1)via 5-Amino-3,4-diphenylthieno[2,3-c]pyridazin-6-carboxamid (3) werden beschrieben.
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Quintela, J.M., Veiga, M.C., Alvarez-Sarandés, R. et al. Synthesis of pyrimido[4′,5′:4,5]thieno[2,3-c]-pyridazine derivatives. Monatsh Chem 127, 537–547 (1996). https://doi.org/10.1007/BF00807079
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DOI: https://doi.org/10.1007/BF00807079