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Reaction of 3-phenyl-5-aminopyrazole with carbon disulfide: A novel synthesis of 3-(3′-phenylpyrazol-5′-yl)-4-phenylpyrazol-2-thione as well as of pyrazolo[3,4-d]thiazole and pyrano[2,3-d]thiazole derivatives

Reaktion von 3-Phenyl-5-aminopyrazol mit Schwefelkohlenstoff: Ein neue Synthese von 3-(3′-Phenylpyrazol-5′-yl)-4-phenylprazol-2-thion sowie von Pyrazolo[3,4-d]thiazol- und Pyrano[2,3-d]thiazolderivaten

  • Organische Chemie Und Biochemie
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Summary

3-Phenyl-5-aminopyrazole (1) reacts with carbon disulfide, followed byin situ reaction with α-haloketones3a–c, to afford5,7a, and7b, respectively. Compounds5 and7 were further utilized for the formation of heterocycles and their fused derivatives.

Zusammenfassung

3-Phenyl-5-aminopyrazol (1) reagiert mit Schwefelkohlenstoff und anschließendin situ mit den α-Halogenketonen3a–c zu5,7a und7b. Die Verbindungen5 und7 wurden weiter zu Heterocyclen und ihren kondensierten Derivaten umgesetzt.

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Authors and Affiliations

  1. Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt

    R. M. Mohareb, H. F. Zohdi & W. W. Wardakhan

Authors
  1. R. M. Mohareb
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  2. H. F. Zohdi
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  3. W. W. Wardakhan
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Mohareb, R.M., Zohdi, H.F. & Wardakhan, W.W. Reaction of 3-phenyl-5-aminopyrazole with carbon disulfide: A novel synthesis of 3-(3′-phenylpyrazol-5′-yl)-4-phenylpyrazol-2-thione as well as of pyrazolo[3,4-d]thiazole and pyrano[2,3-d]thiazole derivatives. Monatsh Chem 126, 1391–1400 (1995). https://doi.org/10.1007/BF00807069

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  • DOI: https://doi.org/10.1007/BF00807069

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