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Synthesis of diterpene glycosides

Synthese von Diterpenglycosiden

  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary

Mono-, di-, and linear triglycosides of a diterpene alcohol, derived from abietic acid and glucose have been synthesized employing peracetylbromo-α-D-glucose (4) and maltose derivatives5 and8 as glycosyl donors. The triglycoside14 exhibits slight haemolytic activity.

Zusammenfassung

Es wird die Synthese von Mono-, Di-, und linearen Triglycosiden aus einem von Abietinsäure abgeleiteten Diterpenalkohol beschrieben. Als Glycosyldonoren wurden neben Peracetobrom-α-D-glucose (4) die Maltosederivate5 und8 verwendet. Das Triglycosid14 zeigt schwache hämolytische Aktivität.

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Authors and Affiliations

  1. Institute of Pharmaceutical Chemistry, University of Graz, A-8010, Graz, Austria

    E. Haslinger, W. Seebacher & R. Weis

Authors
  1. E. Haslinger
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  2. W. Seebacher
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  3. R. Weis
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Haslinger, E., Seebacher, W. & Weis, R. Synthesis of diterpene glycosides. Monatsh Chem 128, 1009–1017 (1997). https://doi.org/10.1007/BF00806967

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  • DOI: https://doi.org/10.1007/BF00806967

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