Abstract
The effect of various doses of acetylcholine (100, 200, and 500 mg/kg) on the mast cells of the albino rat dura mater was studied electron-microscopically and by Falck's luminescence method. Qualitative and quantitative differences were found in the accumulation and elimination of monoamines depending on the dose of acetylcholine used, from which it is concluded that acetylcholine has an activating effect on monoamine secretion.
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Literature Cited
V. N. Gurin, Cholinergic Mechanisms of Regulation of Metabolism [in Russian], Minsk (1975).
V. S. Karedina, G. M. Mukhina, and T. L. Utusikova, in: Current Problems in Nervous Connections [in Russian], Moscow (1976), p. 91.
J. H. Burn and M. J. Rand, Ann. Rev. Pharmacol.,5, 163 (1965).
F. T. Brücke, Klin. Wschr.,14, 7 (1935).
P. M. Vanhoutte and J. Shepherd, Circulat. Res.,32, 259 (1973).
P. M. Vanhoutte, Circulat. Res.,34, 317 (1974).
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Motavkin, P.A., Chertok, V.M. & Shul'ga, S.D. Effect of acetylcholine on mast cells of the dura mater. Bull Exp Biol Med 87, 518–521 (1979). https://doi.org/10.1007/BF00806702
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DOI: https://doi.org/10.1007/BF00806702