Abstract
The distribution of luliberin (luteinizing hormone-releasing hormone, LH-RH) in various organs and tissues of rats was investigated. In the liver, kidneys, duodenum, pancreas, adrenals, and heart of rats a factor analogous to LH-RH in its immunochemical and chromatographic properties was found. The concentration of immunoreactive LH-RH in the liver, kidneys, duodenum, pancreas, and adrenals was about equal (5–7 pg/mg methanol extract obtained from an acetate extract of acetone powder), whereas in the heart it was a little less (2 pg/mg extract). In the blood cells this factor was present in trace amounts. The immunoreactive LH-RH of the visceral organs is either hypothalamic in origin or is synthesized in these organs.
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Isachenkov, V.A., Bakalkin, G.Y. & Tsibezov, V.V. Immunoreactive luliberin in the visceral organs of rats. Bull Exp Biol Med 87, 500–504 (1979). https://doi.org/10.1007/BF00806696
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DOI: https://doi.org/10.1007/BF00806696