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Immunologic cross-reactions between polysaccharides of group A and L streptococci

  • Microbiology and Immunology
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Abstract

By affinity chromatography antibodies were isolated from the sera of rabbits immunized with group A streptococcus on Sepharose immunosorbents containing A-polysaccharide or synthetic β-N-acetylglucosamine. Antibodies obtained from some sera by means of both immunosorbents reacted with polysaccharides of groups A and L. Tests by the immunodiffusion method revealed partial identity of these polysaccharides. It was shown by adsorption of antibodies by polysaccharides of groups A and L that they differ in specificity. These antibodies probably may be aimed at terminal sites of different sizes of the polysaccharide molecule of the group A streptococcus.

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Kolesnikova, V.Y., Borodiyuk, N.A. & Lyampert, I.M. Immunologic cross-reactions between polysaccharides of group A and L streptococci. Bull Exp Biol Med 87, 448–451 (1979). https://doi.org/10.1007/BF00806679

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  • DOI: https://doi.org/10.1007/BF00806679

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