Skip to main content
SpringerLink
Log in

Investigation of bromthymol blue-prealbumin in rat serum during hyperbaric oxygenation

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Disc-electrophoresis studies showed a threefold increase in the concentration of bromthymol blue-prealbumin (BTB-prealbumin; Rm=1.0) in the blood serum of rats after severe convulsions caused by exposure to oxygen in a pressure of 6 atm for 30–35 min. The appearance of a glial S100 protein component and a sevenfold increase in the concentration of an all-organ component of brain BTB-prealbumin in the blood serum of the experimental rats was discovered immunochemically. The consequences of disturbance of the blood—brain barrier for neurospecific and all-organ proteins and also the possibility of discharge of proteins from the brain into the blood stream as in the case of neurophysins during hyperbaric oxygenation are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. I. S. Bashkaev, G. I. Avdeev, and B. S. Sinyakov, Lab. Delo, No. 11, 678 (1969).

    Google Scholar 

  2. I. V. Gannushkina, Immunologic Aspects of Trauma and Cerebrovascular Lesions [in Russian], Moscow (1974).

  3. L. A. Zil'ber (editor), Immunochemical Analysis [in Russian], Moscow (1968), p. 99.

  4. A. A. Krichevskaya, A. A. Sinichkin, L. A. Shcherbina, et al., in: Abstracts of Proceedings of the 6th All-Union Conference on Neurochemistry [in Russian], Leningrad (1972), p. 87.

  5. A. A. Krichevskaya, A. A. Sinichkin, V. N. Prokof'ev, et al., Biokhimiya,42, 230 (1977).

    Google Scholar 

  6. H. Maurer, Disc Electrophoresis [Russian translation], Moscow (1971), p. 58.

  7. V. N. Prokof'ev and A. A. Sinichkin, Biokhimiya,42, 1878 (1977).

    Google Scholar 

  8. A. A. Sinichkin, K. B. Sherstnev, and A. V. Stavitskaya, Izv. Sev-Kavkaz, Nauch. Tsentra Vyssh. Shkoly, Estestven. Nauki, No. 3, 31, (1973).

    Google Scholar 

  9. A. A. Sinichkin, V. N. Prokof'ev, K. B. Sherstnev, et al., Ukr. Biokhim. Zh., No. 4, 429 (1978).

    Google Scholar 

  10. S. B. Lange, M. D. Josphe, C. Lee, et al., in: Sixth International Hyperbaric Congress, Aberdeen (1977), p. 50.

  11. O. H. Lowry, N. J. Rosebrough, A. L. Farr, et al., J. Biol. Chem.,193, 265 (1951).

    Google Scholar 

  12. R. Walter, Ann. New York Acad. Sci.,248, 1 (1975).

    Google Scholar 

Download references

Authors
  1. A. A. Sinichkin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. N. Prokof'ev
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sinichkin, A.A., Prokof'ev, V.N. Investigation of bromthymol blue-prealbumin in rat serum during hyperbaric oxygenation. Bull Exp Biol Med 87, 427–430 (1979). https://doi.org/10.1007/BF00806672

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00806672

Key Words

Search

Navigation