Role of increased peripheral vascular resistance in burn shock

  • L. L. Shik
  • N. A. Len'kova
Pathological Physiology and General Pathology

Abstract

In intact rabbits and rabbits with exclusion of the aortic and carotid sinus reflexogenic zones the effects of lethal burn trauma were studied on indices of the hemodynamics and respiration. Similar changes were found in the cardiac output and total oxygen consumption in the rabbits of the two groups. By contrast with intact animals, in rabbits with exclusion of the reflexogenic zones burns did not lead to any sharp rise of peripheral vascular resistance. The systemic arterial pressure fell correspondingly in these animals by a much greater degree than in the intact rabbits. The survival period of the denervated rabbits after burns was shorter than that of the intact rabbits. It is concluded that the increase in the peripheral vascular resistance in burn shock is of a reflex compensatory nature.

Key Words

burn shock peripheral vascular resistance hemodynamics 

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Literature Cited

  1. 1.
    N. I. Kochetygov, Burns [in Russian], Leningrad (1973).Google Scholar
  2. 2.
    V. B. Lemus and A. I. Ozerskii, in: Abstracts of Proceedings of the 1st All-Union Conference on Thermal Burns [in Russian], Moscow (1972), pp. 125–127.Google Scholar
  3. 3.
    N. A. Len'kova, Byull. Éksp. Biol. Med., No. 5, 14 (1974).Google Scholar
  4. 4.
    N. A. Len'kova, Byull. Éksp. Biol. Med., No. 9, 24 (1974).Google Scholar
  5. 5.
    B. P. Sandirskii, in: Problems in Burn Pathology [in Russian], Gor'kii (1970), pp. 200–205.Google Scholar
  6. 6.
    N. A. Fedorov, in: Pathological Physiology of Extremal States [in Russian], Moscow (1973), pp. 180–200.Google Scholar
  7. 7.
    L. L. Shik, A. N. Kuznetsova, and B. I. Lektorskii, in: Proceedings of the 4th Scientific Conference on the Problem of Burns [in Russian], Leningrad (1965), pp. 276–278.Google Scholar
  8. 8.
    M. J. Asch, R. J. Feldman, H. L. Walker, et al., Ann. Surg.,178, 218 (1973).Google Scholar
  9. 9.
    G. Birke, S. O. Liljedahl, and H. Linderholm, Acta Chir. Scand.,116, 370 (1959).Google Scholar
  10. 10.
    E. L. Dobson and G. E. Warner, Circulat. Res.,5, 69 (1957).Google Scholar
  11. 11.
    H. Fozzard, Ann. Surg.,154, 113 (1961).Google Scholar
  12. 12.
    J. P. Gilmore and S. W. Handford, J. Appl. Physiol.,8, 393 (1956).Google Scholar
  13. 13.
    C. Jelenko, W. R. O'Kelley, H. C. Byrd, et al., J. Surg. Res.,20, 7 (1976).Google Scholar
  14. 14.
    D. D. Michie, R. S. Goldsmith, A. D. Mason et al., J. Trauma,3, 111 (1963).Google Scholar
  15. 15.
    J. A. Moncrief, Ann. Surg.,164, 723 (1966).Google Scholar
  16. 16.
    D. A. Pruitt, A. D. Mason, and J. A. Moncrief, J. Trauma,11, 36 (1971).Google Scholar
  17. 17.
    S. Sevitt, Burns. Pathology and Therapeutic Application, London (1957).Google Scholar
  18. 18.
    S. Wetterlin, B. F. Ericsson, and K. F. Aronsen, Eur. Surg. Res. (Basel),8, 545 (1976).Google Scholar

Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • L. L. Shik
  • N. A. Len'kova

There are no affiliations available

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