Role of increased peripheral vascular resistance in burn shock

  • L. L. Shik
  • N. A. Len'kova
Pathological Physiology and General Pathology


In intact rabbits and rabbits with exclusion of the aortic and carotid sinus reflexogenic zones the effects of lethal burn trauma were studied on indices of the hemodynamics and respiration. Similar changes were found in the cardiac output and total oxygen consumption in the rabbits of the two groups. By contrast with intact animals, in rabbits with exclusion of the reflexogenic zones burns did not lead to any sharp rise of peripheral vascular resistance. The systemic arterial pressure fell correspondingly in these animals by a much greater degree than in the intact rabbits. The survival period of the denervated rabbits after burns was shorter than that of the intact rabbits. It is concluded that the increase in the peripheral vascular resistance in burn shock is of a reflex compensatory nature.

Key Words

burn shock peripheral vascular resistance hemodynamics 


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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • L. L. Shik
  • N. A. Len'kova

There are no affiliations available

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