Localization of specific antigen in organs of animals inoculated with different batches of live measles vaccine
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The location of the specific antigen in the walls of the cerebral blood vessels and in neurons and glial cells was studied by an immunofluorescence method in newborn albino rats and Syrian hamsters inoculated subcutaneously with four different batches of live measles vaccine. Pathomorphological examination of the brain revealed mainly vascular disorders. The results are evidence of the presence of residual neurotropism in attenuated measles virus (strain L-16).
Key Wordsattenuated measles virus immunofluorescence
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- 1.V. N. Bondarev, M. A. Dadiomova, and R. M. Pratusevich, in: Neuroviral and Infectious-Allergic Diseases in Children [in Russian], Kiev (1968), p. 76.Google Scholar
- 2.V. P. Braginskaya and A. F. Sokolova, Pediatriya, No. 1, 26 (1974).Google Scholar
- 3.A. A. Dutova, in: Current Problems in Pediatrics [in Russian], Karaganda (1970), p. 148.Google Scholar
- 4.Yu. F. Kubitsa (ed.), Immunofluorescence [in Russian], Moscow (1967).Google Scholar
- 5.V. A. Romanov, L. P. Gorshunova, and R. V. Berezhkova, Byull. Éksp. Biol. Med., No. 10, 1232 (1976).Google Scholar
- 6.S. N. Terekhova, L. M. Chudnaya, A. B. Shekhter, et al., in: Living Antimeasles Vaccine [in Russian], Leningrad (1965), p. 192.Google Scholar
- 7.A. T. Ul'masov, Z. T. Shaikhanova, and I. L. Kozlova, in: Specific Measles Prophylaxis [in Russian], Leningrad (1970), p. 51.Google Scholar
- 8.L. M. Chudnaya, “Specific measles vaccine prophylaxis in the Ukraine,” Author's Abstract of Doctoral Dissertation, Moscow (1971).Google Scholar