Abstract
The anterior lobe of the pituitary (ALP) of rats exposed to general cooling to −10°C for 6 min was investigated by histological and autoradiographic methods. The diurnal cycle of changes in the functional state of the glandular cells of ALP, the number of mitoses, and the number of labeled cells synthesizing DNA was examined 3, 6, 12, 18, and 24 h after cooling. Marked activation of thyrotrophs and doubling of the number of mitoses were observed 12 h after cooling, with no change in the index of labeled cells in the course of 24 h. The results showed that the stressor response to cold in rats is characterized by potentiation of the thyrotrophic function and by acceleration of mitosis in the cells of ALP.
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Monastyrskaya, B.I., Silina, A.G. Response of anterior pituitary cells after acute cooling in rats. Bull Exp Biol Med 85, 804–806 (1978). https://doi.org/10.1007/BF00806173
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DOI: https://doi.org/10.1007/BF00806173