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Thermostable antigens of malignant tumors and normal tissues of experimental animals

  • Oncology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Thermostable antigens (TA) were found by the gel precipitation test and by immunoelectrophoresis in malignant tumors of muscle tissue induced by dimethylbenzanthracene, and in the amniotic fluid of 8–12-day embryos and certain normal organs of adult Wistar rats. Relative tissue specificity of these antigens was demonstrated, on the one hand, for tumors, amniotic fluid, and the uterus, and on the other hand for the lung, spleen, and serum. TA detected in tumors and amniotic fluid by immunoelectrophoresis are located in the zones of α- and α1-globulins.

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Lomakin, M.S., Larin, A.S. & Maiskii, I.N. Thermostable antigens of malignant tumors and normal tissues of experimental animals. Bull Exp Biol Med 85, 795–798 (1978). https://doi.org/10.1007/BF00806170

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  • DOI: https://doi.org/10.1007/BF00806170

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