Abstract
The effect of β-adrenergic stimulators adrenalin and isoproterenol and of the β-adrenergic blocker propranolol on lymphocytosis and on the macrophage adhesion inhibition reaction was studied in vivo and in vitro on sensitized and intact guinea pigs and Wistar rats. Adrenalin and isoproterenol were shown to inhibit the reaction of the antigen with both sensitized and intact cells. Propranolol abolishes the protective effect of adrenalin and isoproterenol and restores the sensitivity of the cells to antigen.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
N. N. Golubeva, I. K. Vardanyan, and V. F. Golubeva, in: Neurohumoral and Pharmacological Correction of Immune Reactions Under Experimental and Clinical Conditions [in Russian], Leningrad (1975), p. 14.
M. M. Kapichnikov and L. F. Lazarenko, in: Immunoreactivity of the Organism [in Russian], Kaliningrad and Tallin (1973), pp. 105–107.
U. Ernstrom and O. Soder, Clin. Exp. Immunol.,21, 131 (1975).
S. P. Galant and R. A. Remo, J. Immunol.,114, 512 (1975).
J. W. Hadden, E. M. Hadden, et al., Cell. Immunol.,108, 583 (1970).
J. W. Hadden et al., Int. Arch. Allergy,40, 526 (1971).
W. T. Halliday and S. Miller, Int. J. Cancer,9, 447 (1972).
T. P. Stossel, New Engl. J. Med.,290, 717 (1974).
T. B. Strom and C. B. Carpenter, J. Exp. Med.,138, 381 (1973).
Rights and permissions
About this article
Cite this article
Kozlov, V.K., Arkhangel'skaya, S.L. & Vasil'eva, E.F. β-Adrenorecptors on the surface membranes of lymphocytes and macrophages. Bull Exp Biol Med 85, 792–794 (1978). https://doi.org/10.1007/BF00806169
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00806169