Abstract
The quantitative and qualitative composition of the leukocytes and dehydrogenase activity of the lymphocytes were determined in blood entering and leaving the transplanted heart at different times after grafting in dogs. A decrease in the lymphocyte count in blood flowing from the grafted heart was found, on account of retention of the lymphocytes in the graft; the activities of the mitochondrial dehydrogenases also were reversed as the result of contact of the lymphocytes with the foreign antigens of the transplanted heart. It is suggested that the mechanism of reversal is connected with the functions of the lymphocytes as immunocompetent cells.
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Frolova, M.A., Tregerova, V. & Bol'shukhina, L.A. Lymphocyte response in the early period after heart transplantation. Bull Exp Biol Med 85, 770–773 (1978). https://doi.org/10.1007/BF00806161
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DOI: https://doi.org/10.1007/BF00806161