Skip to main content
SpringerLink
Log in

Character and frequency of pathological changes in the solitary rat kidney after removal of the other kidney in old age

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

One kidney was removed from male rats weighing 500–850 g; the remaining kidney underwent compensatory hypertrophy and, after 1–2 months, it was larger (index of hypertrophy 70–92%) in rats weighing 700–850 g than in animals weighing 500–600 g (56–58%). Histological investigation showed that this marked hypertrophy of the solitary kidney in old rats was not the result of disease of the organ, for pathological changes such as are sometimes found in intact and hypertrophied kidneys were found in only 38 of 223 animals. The results suggest that the ability of the kidneys to undergo, compensation and regeneration is not reduced in old age.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. M. I. Moldavskii, Arkh. Patol., No.4, 91 (1976).

    Google Scholar 

  2. A. Ya. Pytel' and M. A. Grishin, Diseases of the Solitary Kidney [in Russian], Moscow (1973).

  3. V. V. Serov, The Morphological Bases of Immunopathology of the Kidneys [in Russian], Moscow (1968).

  4. V. F. Sidorova, Age and the Regenerative Power of Organs in Mammals [in Russian], Moscow (1976).

  5. V. F. Sidorova and V. D. Gorbunova, Byull. Éksp. Biol. Med., No. 11, 1394 (1976).

    Google Scholar 

  6. A. I. Strukov, Pathological Anatomy [in Russian], Moscow (1967).

  7. V. V. Frol'kis, Aging and the Biological Powers of the Organism [in Russian], Moscow (1975).

  8. S. Dunnil and W. Halley, J. Pathol.,110, 113 (1973).

    Google Scholar 

  9. U. Garcia-Cacerer, Am. J. Pathol.,35, 755 (1959).

    Google Scholar 

  10. J. Hanker, J. Preece, and E. MacRae, Histochemistry (Berlin),44, 225 (1975).

    Google Scholar 

  11. T. Morita, J. Suzuki, and J. Churg, Am. J. Pathol.,49, 349 (1973).

    Google Scholar 

  12. F. Verzar, in: Compensatory and Renal Hypertrophy (ed. by W. Nowinski and R. Goss), New York (1969), p. 271.

Download references

Authors
  1. V. F. Sidorova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. D. Gorbunova
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sidorova, V.F., Gorbunova, V.D. Character and frequency of pathological changes in the solitary rat kidney after removal of the other kidney in old age. Bull Exp Biol Med 84, 1350–1353 (1977). https://doi.org/10.1007/BF00805905

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00805905

Key Words

Search

Navigation