Abstract
The dynamics of DNA synthesis in fibroblasts of granulation tissue of wounds was investigated in adults mice, some of which were given potassium orotate. Regions of the wound in animals receiving 0.2 ml of a 2% solution of potassium orotate and in control animals were investigated autoradiographically daily. Under the influence of potassium orotate fibroblasts took up DNA synthesis more frequently: Increased proliferative activity of these cells was found during stimulation of wound healing.
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Dudnikova, G.N. DNA synthesis by fibroblasts of granulation tissue during stimulation of wound healing. Bull Exp Biol Med 84, 1338–1340 (1977). https://doi.org/10.1007/BF00805901
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DOI: https://doi.org/10.1007/BF00805901