Abstract
Like strophanthin K, ethacrynic acid increases the sodium concentration and reduces the potassium concentration in frog urinary bladder tissue, with the result that potassium secretion is reduced; furosemide does not change these concentrations. The results point to differences in the intracellular action of furosemide and ethacrynic acid.
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Shakhmatova, E.I., Natochin, Y.V. Effect of furosemide and ethacrynic acid on sodium transport and potassium secretion. Bull Exp Biol Med 84, 1296–1298 (1977). https://doi.org/10.1007/BF00805889
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DOI: https://doi.org/10.1007/BF00805889