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Mechanism of disturbances of energy formation in acute ischemia of the liver

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Respiration of rat liver mitochondria after the addition of ischemic toxin to the incubation medium was compared with respiration of mitochondria isolated from ischemic rat liver. The changes in respiration in both cases could be prevented by preliminary addition of dithiothreitol and reduced by subsequent addition of cytochrome c or dithiothreitol to the incubation medium. The similarity between the mechanisms of disturbance of energy formation is postulated.

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Levandovskii, I.V., Lyakhovich, V.V., Panov, A.V. et al. Mechanism of disturbances of energy formation in acute ischemia of the liver. Bull Exp Biol Med 84, 1274–1276 (1977). https://doi.org/10.1007/BF00805882

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  • DOI: https://doi.org/10.1007/BF00805882

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