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Bulletin of Experimental Biology and Medicine

, Volume 84, Issue 3, pp 1268–1270 | Cite as

Phospholipids and cholesterol of the brain and spinal cord of guinea pigs poisoned with tricresyl phosphate

  • N. P. Taranova
  • É. Illiger
Biochemistry and Biophysics
  • 14 Downloads

Abstract

The content of phospholipids and of total, free, and esterified cholesterol in the brain and spinal cord of guinea pigs with severe neuroparalytic signs of poisoning caused by intradermal injection of tricresyl phosphate (TCP) was investigated. No change was found in the content of phospholipids and total cholesterol in either the brain or the spinal cord, but accumulation of cholesterol esters—the characteristic degradation products of myelin sheaths-was observed.

Key Words

tricresyl phosphate phospholipids cholesterol demyelination spinal cord 

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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • N. P. Taranova
  • É. Illiger

There are no affiliations available

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