Abstract
The course of the primary immunologic response after unilateral destruction of the posterior hypothalamic nuclei is atypical, antibody synthesis is depressed, antibodies can be detected later, and the number of antibody-forming cells is reduced. Electron-microscopic investigations revealed a decrease in the functional activity of the plasma cells, a relative predominance of young undifferentiated cells of the plasma-cell series, and a decrease in the number of mature differentiated forms, evidently reflecting the reduced rate of differentiation of immunocompetent cells.
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Laboratory for Biophysical Problems, Department of Histology, Tashkent Medical Institute. Department of Pathophsiology and Division of Immunity and Allergy, Central Research Laboratory, Rostov Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 79, No. 1, pp. 78–83, January, 1975.
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Kishkovskaya, O.V., Zufarov, K.A., Saakov, B.A. et al. Morphological and submicroscopic characteristics of the primary immunologic response after destruction of the posterior hypothalamic nuclei. Bull Exp Biol Med 79, 78–82 (1975). https://doi.org/10.1007/BF00805512
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DOI: https://doi.org/10.1007/BF00805512