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Focal deaggregation of myofibrils in acute metabolic lesions of the somatic muscles

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Target electron-microscopic and polarization-optical investigations were made of the skeletal muscles of rats and rabbits after injection of toxic substances and experimental acute ischemia of the limbs. Besides contraction injuries, two types of focal deaggregation of the myofibrils are described. The first arises on a basis of relaxation and is manifested as total deaggregation and lysis of the myofibrils; in the second form lysis arises in the partially contracted fiber and begins in the I-discs, leading to diastasis of the A-discs. Foci of the first type are characteristic mainly of white fibers, those of the second type of red fibers.

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Authors
  1. S. F. Tsellarius
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  2. Yu. G. Tsellarius
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Tsellarius, S.F., Tsellarius, Y.G. Focal deaggregation of myofibrils in acute metabolic lesions of the somatic muscles. Bull Exp Biol Med 79, 71–74 (1975). https://doi.org/10.1007/BF00805510

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  • DOI: https://doi.org/10.1007/BF00805510

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