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Effect of stimulators of immunoglobulin biosynthesis on macrophagal transformation of lymphocytes

  • Immunology and Microbiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of pyrogenal and adjuvant of the Freund type on the transformation of blood lymphocytes into macrophages was studied. Experiments were carried out on rabbits using the method of lymphocyte cultures in vitro. These stimulators of immunogenesis were shown to increase the intensity of transformation of the lymphocytes in culture. The action of pyrogenal and of Freund's complete adjuvant was manifested during the first day after its addition. Correlation is postulated between the ability of lymphocytes to undergo conversion into macrophages and the formation of the immunologic response of the organism.

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Authors
  1. T. A. Demchenko
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  2. B. G. Avetikyan
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Demchenko, T.A., Avetikyan, B.G. Effect of stimulators of immunoglobulin biosynthesis on macrophagal transformation of lymphocytes. Bull Exp Biol Med 79, 54–56 (1975). https://doi.org/10.1007/BF00805505

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  • DOI: https://doi.org/10.1007/BF00805505

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