Abstract
Methyluracil in doses of 1 to 50 μg/ml increased the total nucleic acid content in the nulcei and protein content in the cytoplasm of HEp-2 cells. A dose of 20 μg/ml gave a gradual increase in the nucleic acid concentration in the cells from 122 to 197%. A relatively stable increase in protein with all durations of exposure was produced by a dose of 30 μg/ml (132–145%). The results suggest an increase in the intensity of cell metabolism under the influence of methyluracil.
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Rusakov, V.I., Kuchkin, V.T. Effect of methyluracil on the protein and nucleic acid content in HEp-2 cells. Bull Exp Biol Med 79, 36–37 (1975). https://doi.org/10.1007/BF00805499
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DOI: https://doi.org/10.1007/BF00805499