Inhibition of the action of tetanus toxin by vitamin B₁

Abstract

Experiments on rabbits showed that preliminary injections of vitamin B₁ and their continuation after injection of tetanus toxin increased the resistance of the animals to tetanus. A more marked protective effect was observed if the tetanus toxin was injected into the rabbits in vitamin B₁ solution. Injection of the vitamin 2 h after the toxin led to a tendency toward an increase in resistance.