Growth and proliferation of the endothelium of the bone marrow sinusoids in tissue cultures

  • M. G. Shcherbakova
Experimental Biology


The bone marrow of the femur of adult rabbits was cultivated in Carrel's flasks with passage within a period of more than two months. The endothelium of the sinusoids, as distinct from the reticular and fibroblast-like elements of the connective tissue, proliferated by means of the membranes of closely-arranged cells similarly to the endothelium of larger vessels, retaining a characteristic appearance during the entire period of cultivation. The term “reticulo-endothelial cells” which is incorrect in the author's view is discussed on the basis of the author's own data and analysis of the literature data, since the reticular and endothelial cells show different predetermined properties in the cultures and fail to transform into one another. The endothelium of the capillaries and arterioles during the early days of cultivation grows from the central piece as vascular buds, coalescing later with the membranes of sinusoid endothelium.


Public Health Bone Marrow Endothelial Cell Tissue Culture Connective Tissue 
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Copyright information

© Consultants Bureau 1967

Authors and Affiliations

  • M. G. Shcherbakova

There are no affiliations available

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