Skip to main content
Log in

Effect of combined administration of para-aminobenzoic acid (PABA) and β-sitosterol on the course of experimental atheroslerosis in rabbits

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

This research is devoted to the study of the combined effect of 2 preparations (PABA and β-sitostyrene) with different mechanisms of the antisclerotic effect. In a comparative estimation of the basic indices in control and test animals (cholesterol and phospholipid content of the blood serum, cholesterol level in the liver and aorta, as well as number of lipids in the aortic wall) it was found that injection of the above combination of preparations prevented disturbance of the cholesterol-lecithin balance in test animals to a considerable extent in spite of a prolonged cholesterol administration (20 weeks).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. K. A. Meshcherskaya, G. P. Borodina, and N. P. Koroleva, et al., Farmakol. i toksikol., 5 (1959), p. 434.

    Google Scholar 

  2. A. F. Ryzhova, Byull. éksper. biol., 7 (1963), p. 52.

    Google Scholar 

  3. A. M. Khaletskii, Med. prom. SSSR, 11 (1961), p. 32.

    Google Scholar 

  4. N. A. Yushchenko, Byull. éksper. biol., 3 (1959), p. 31.

    Google Scholar 

  5. W. W. Davis, Trans. New York Acad. Sci., 18 (1955), p. 123.

    Google Scholar 

  6. M. Fraser and F. Gardner, Proc. roy. Soc. B., 82, (1910), p. 559.

    Google Scholar 

  7. H. H. Hernander and I. L. Chaikoff, Proc. Soc. exp. Biol. (New York) 87 (1954), p. 541.

    Google Scholar 

  8. D. W. Peterson, Proc. Soc. exp. Biol. (New York), 78 (1951), p. 143.

    Google Scholar 

  9. R. Schoenheimer and Heylers-Hoppe. Z. physiol. Chem., 180, (1929), p. 1.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ryzhova, A.F. Effect of combined administration of para-aminobenzoic acid (PABA) and β-sitosterol on the course of experimental atheroslerosis in rabbits. Bull Exp Biol Med 60, 926–928 (1965). https://doi.org/10.1007/BF00805048

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00805048

Keywords

Navigation