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Effect of transplantation of lymphocytes and bone marrow cells on immune response during immunization of mice with low or high reactivity to the antigen

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Mice of strains C57BL and CBA, with low and high reactivity respectively to immunization with sheep's red cells, received injections of syngeneic lymphocytes or bone marrow cells. Transplantation of syngeneic cells into C57BL mice increased the production of cells forming antibodies against sheep's red cells, but had a depressant effect in CBA mice. The different effects of transplantation of lymphocytes and bone marrow cells on the immune response, depending on the recipient's genotype, are discussed.

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Authors and Affiliations

  1. Academy of Medical Sciences of the USSR, USSR

    R. V. Petrov (Corresponding Member)

Authors
  1. R. V. Petrov
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  2. R. M. Khaitov
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  3. A. A. Batyrbekov
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Additional information

Moscow. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 3, pp. 335–337, March, 1976.

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Petrov, R.V., Khaitov, R.M. & Batyrbekov, A.A. Effect of transplantation of lymphocytes and bone marrow cells on immune response during immunization of mice with low or high reactivity to the antigen. Bull Exp Biol Med 81, 396–398 (1976). https://doi.org/10.1007/BF00804930

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  • DOI: https://doi.org/10.1007/BF00804930

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