Abstract
The anabolic steroid retabolil, in chronic experiments on dogs (2 mg/kg for 7 days) and rats (5 mg/kg for 7 days) increased the renal tubular secretion of diodone. At the same time the concentration of protein and RNA in the renal cortex was increased, which could indicate the protein nature of the carrier taking part in renal secretory transport.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
E. B. Berkhin, in: Proceedings of the Eleventh Congress of the I. P. Pavlov All-Union Physiological Society [in Russian], Vol. 2, Leningrad (1970), p. 302.
B. Ya. Varshavskii, I. G. Littig, and V. I. Abaurova, Fiziol. Zh. SSSR, No. 4, 656 (1974).
A. V. Karakashov and E. P. Vichev, Micromethods in the Clinical Laboratory [in Russian], Sofia (1968), p. 146.
Yu. V. Natochin, in: The Physiology of the Kidney [in Russian], Leningrad (1972), p. 83.
A. S. Spirin, Biokhimiya, No. 5, 656 (1958).
B. Bak, C. Brun, and F. Roaschon, Acta Med. Scand.,114, 271 (1943).
O. H. Lowry, N. J. Rosebrough, A. L. Farr, et al., J. Biol. Chem.,193, 265 (1951).
G. Schmidt and S. Thannhauser, J. Biol. Chem.,161, 83 (1945).
H. W. Smith, The Kidney, New York (1951).
L. G. Wesson, Physiology of the Human Kidney, New York (1969).
Rights and permissions
About this article
Cite this article
Kuvshinnikova, V.A. Effect of retabolil on tubular secretion of the kidneys. Bull Exp Biol Med 81, 364–366 (1976). https://doi.org/10.1007/BF00804921
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00804921