Abstract
The effect of cylic AMP, ACTH, and glucose on formation of the enzyme chloramphenicol acetyltransferase by cells ofEscherichia coli CSH-2/R222 andE. coli WZ-78/R222 (cya855) was investigated. Glucose was shown to reduce synthesis of the enzyme inE. coli CSH-2/R222 by inducing catabolite repression; this could be overcome by 5 mM cyclic AMP and 1000 μg/ml ACTH. Synthesis of the enzyme inE. coli WZ-78/R222 was resistant to catabolite repression and ACTH did not stimulate the synthesis of chloramphenicol acetyltransferase by this strain.
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Boichenko, M.N., Aniskin, E.D. Investigation of chloramphenicol acetyltransferase formation byEscherichia coli K-12 cells after changes in intracellular cyclic AMP concentration. Bull Exp Biol Med 81, 338–340 (1976). https://doi.org/10.1007/BF00804912
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DOI: https://doi.org/10.1007/BF00804912