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Effect of toxin of burned skin on the state of the hemodynamics in rats

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Toxin for burned rat skin, purified immunochemically, possesses definite physiological activity against the cardiovascular system of homologous animals. If injected into the blood stream, the toxin lowers the systemic arterial pressure within 2 h from 125±7 to 74±8 mm Hg. The development of systemic hypotension is accompanied by secondary disorders of the microcirculation in the mesentery of the small intestine, characterized by constriction of the arterioles, slowing of the blood flow along the venules, and reduction of the capillary blood flow.

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Authors
  1. V. P. Matvienko
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  2. B. E. Movshev
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Matvienko, V.P., Movshev, B.E. Effect of toxin of burned skin on the state of the hemodynamics in rats. Bull Exp Biol Med 81, 310–312 (1976). https://doi.org/10.1007/BF00804903

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  • DOI: https://doi.org/10.1007/BF00804903

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