Abstract
Thyroxine and triiodothyronine in the thyroid gland of encephalectomized and intact fetuses of rats with normal and prolonged gestation period were determined by a radioisotope method. Encephalectomy on 19-day fetuses had no significant effect on the concentration of thyroid hormone in the gland 2 and 4 days after the operation. The results are evidence against hypothalamic control of pituitary thyrotropic function in the prenatal development of rats.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
M. S. Mitskevich and O. N. Rumyantseva, Ontogenez,3, 376 (1972).
M. S. Mitskevich, O. N. Rumyantseva, E. V. Proshlyakova, et al., Ontogenez,1, 631 (1970).
V. M. Samsonova, “The role of the paraventricular nuclei in hypothalamic regulation of the pituitary-thyroid gland system,” Author's Abstract of Candidate's Dissertation, Moscow (1968).
S. A. D'Angelo and N. R. Wall, Neuroendocrinology,9, 197 (1971).
P. M. Conklin, W. Y. Schindler, and S. F. Hull, Neuroendocrinology,11, 197 (1973).
J. H. Dussault and F. Labrie, Endocrinology,97, 1321 (1975).
A. Kojihara, A. Kojima, T. Ohava, et al., Endocrinology,90, 592 (1972).
A. Kojima et al., Endocrinology,94, 1133 (1974).
Rights and permissions
About this article
Cite this article
Proshlyakova, E.V., Chandrasekkhar, K. & Rumyantseva, O.N. Determination of thyroxine and triiodothyronine in the thyroid gland of encephalectomized rat fetuses. Bull Exp Biol Med 84, 1762–1763 (1977). https://doi.org/10.1007/BF00804830
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00804830