Bulletin of Experimental Biology and Medicine

, Volume 84, Issue 6, pp 1750–1753 | Cite as

Antitumor action of glycopeptides from the cell wall of Lactobacillus bulgaricus

  • I. G. Bogdanov
  • V. T. Velichkov
  • A. I. Gurevich
  • P. G. Dalev
  • M. N. Kolosov
  • V. P. Mal'kova
  • I. B. Sorokina
  • L. N. Khristova
Oncology

Abstract

The antitumor action of the substance blastolysin, the main components of which are glycopeptide fragments from the cell wall ofLactobacillusbulgaricus, was studied. Blastolysin exhibits a specific antitumor effect against sarcoma S-180, leukemia P-388, plasmacytoma MOPC-315, adenocarcinoma AKATOL, melanosarcoma B-16, carcinoma LLC, and spontaneous tumors of mice. It has low toxicity, does not depress hematopoiesis, and in the character of its action on tumor tissue it differs essentially from known chemotherapeutic preparations.

Key Words

chemotheraphy of tumors glycopeptides immunity 

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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • I. G. Bogdanov
  • V. T. Velichkov
  • A. I. Gurevich
  • P. G. Dalev
  • M. N. Kolosov
  • V. P. Mal'kova
  • I. B. Sorokina
  • L. N. Khristova

There are no affiliations available

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