Bulletin of Experimental Biology and Medicine

, Volume 84, Issue 6, pp 1722–1724 | Cite as

Reaction of antibodies to antigens of group A streptococcus with fibroblasts of interstitial connective tissue of the human heart

  • G. A. Ugryumova
  • I. M. Lyampert
  • V. Yu. Kolesnikova
  • V. P. Bukhova
Microbiology and Immunology


The sera of rabbits immunized by fractions containing nontype-specific group A streptococcal antigens, belonging to cell wall proteins, were studied by the indirect immunofluorescence method. Antibodies reacting with fibroblasts of the interstitial connective tissue of the human heart were found in the sera. On the basis of the results of absorption experiments it is postulated that a cross-reacting antigen common with an antigen of the fibroblasts is present in some hydrochloric acid extracts obtained from streptococci of groups A and C.

Key Words

cross-reacting antigens antibodies streptococcous fibroblasts myocardium 


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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • G. A. Ugryumova
  • I. M. Lyampert
  • V. Yu. Kolesnikova
  • V. P. Bukhova

There are no affiliations available

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