Bulletin of Experimental Biology and Medicine

, Volume 87, Issue 4, pp 304–306 | Cite as

Effect of developing insulin hypoglycemia on monosynaptic spinal reflexes in cats

  • Yu. P. Pushkarev
Pathological Physiology and General Pathology


Acute experiments on anesthetized and spinal cats showed that deepening insulin hypoglycemia causes inhibition of rhythmic monosynaptic EPSPs of motoneurons in the lumbar region of the spinal cord. In the initial period of hypoglycemia (a fall of the blood sugar to 50–60 mg%) the progressive decrease in the efficiency of trans-synaptic processes was not caused by pre-or postsynaptic inhibition or by depression and was due to exhaustion of the operative fraction of mediator. In deeper hypoglycemia the functions of the postsynaptic formation of the monosynaptic spinal reflex arc are disturbed.

Key Words

spinal cord monosynaptic potentials of motoneurons insulin hypoglycemia 


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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • Yu. P. Pushkarev

There are no affiliations available

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