Effect of various doses of progesterone and estrogens on embryonic development in ovariectomized rats
- 13 Downloads
Experiments were carried out on pregnant noninbred rats. The animals were ovariectomized on the 8th day of pregnancy, continuation of which was ensured by injection of the principal ovarian hormones: estradiol dipropionate, folliculin, estriol, and progesterone in various combinations. The animals were killed on the 21st day of pregnancy, and the fetuses were removed and inspected externally. The results showed that ovariectomy, carried out on the 8th day of pregnancy, interrupted its course. Normal embryogenesis took place only after injection of all the principal ovarian hormones.
Key wordspregnancy embryogenesis ovariectomy progesterone estrogens
Unable to display preview. Download preview PDF.
- 1.M. L. Dogonadze, The Organization of the Early Detection and Effectiveness of Functional Treatment of Congenital Dislocation of the Hip. Author's Abstract of Doctoral Dissertation, Tbilisi (1972).Google Scholar
- 2.I. L. Kurdovanidze and M. K. Tedeshvili, in: Proceedings of a Republican Scientific Conference of Junior Biological Research Workers and Postgraduate Students [in Russian], Tbilisi (1970), p. 161.Google Scholar
- 3.N. S. Mamulashvili, The Role of the Various Fractions of Female Sex Hormone in Ovarian-Pituitary Interrelationships. Author's Abstract of Candidate's Dissertation, Tbilisi (1968).Google Scholar
- 4.V. G. Orlova, Method of Determining the Excretion of Estriol and its Diagnostic Important in Prematurity. Author's Abstract of Candidate's Dissertation, Smolensk (1966).Google Scholar
- 5.O. N. Savchenko, Ovarian Hormones and Gonadotropic Hormones [in Russian], Leningrad (1967).Google Scholar
- 6.L. Andren et al., Acta Radiol. (Stockholm),55, 217.Google Scholar
- 7.J. G. Barlow, Proc. Roy. Soc. Med.,59, 1103 (1966).Google Scholar
- 8.B. J. Brown, Aust. J. Exp. Biol. Med. Sci.,39, 345 (19 1)Google Scholar
- 9.G. Kaiser, Beitr. Orthop. Traum.,4, 206 (1967).Google Scholar