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Bulletin of Experimental Biology and Medicine

, Volume 78, Issue 5, pp 1281–1283 | Cite as

Effect of adrenalectomy on enzyme activity in the mucous membrane of the rat small intestine

  • K. Rakhimov
  • U. Z. Kadyrov
  • B. Zaripov
Biochemistry and Biophysics
  • 11 Downloads

Abstract

Bilateral adrenalectomy leads to a decrease in the invertase, pepidase, and alkaline phosphatase activity in the mucous membrane of the rat small intestine. Monoglyceride-lipase activity is increased under the circumstances in the great majority of cases. The character of the change in activity of the various enzymes also depends on the time elapsing after adrenalectomy. Compensation of the mineralocorticoid or glucocorticoid deficiency by administration of sodium chloride to the adrenalectomized rats or by injection of hydrocortisone abolished the observed effects only partially.

Key Words

adrenalectomy in rats small intestine enzymes of the mucous membrane hydrocortisone 

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Literature Cited

  1. 1.
    G. A. Bulbuk, Fiziol. Zh. SSSR, No. 5, 607 (1968).Google Scholar
  2. 2.
    Yu. N. Kolesnikov, in: Problems in Medical Theory, Clinical Practice, and Balneotherapy [in Russian], No. 4, Simferopol' (1971), p. 80.Google Scholar
  3. 3.
    A. M. Ugolev, Contact Digestion, Semisubstrate Processes, Organization and Regulation [in Russian], Leningrad (1972).Google Scholar
  4. 4.
    A. M. Ugolev and N. N. Iezuitova, in: Investigations of the Digestive Apparatus in Man [in Russian], Leningrad (1969), p. 192.Google Scholar
  5. 5.
    A. M. Ugolev and N. N. Timofeeva, in: Investigations of the Digestive Apparatus in Man [in Russian], Leningrad (1969), p. 178.Google Scholar
  6. 6.
    A. M. Ugolev and M. Yu. Chernyakhovskaya, in: Investigations of the Digestive Apparatus in Man [in Russian], Leningrad (1969), p. 183.Google Scholar
  7. 7.
    J. J. Deren, in: Handbook of Physiology, Sec. 6, Vol. 3, Washington (1968), p. 262.Google Scholar
  8. 8.
    R. G. Doell and N. Kretchmer, Science,143, 42 (1964).Google Scholar
  9. 9.
    C. H. Fiske and G. Subbarow, J. Biol. Chem.,66, 375 (1925).Google Scholar
  10. 10.
    O. Koldovsky, Development of the Function of the Small Intestine in Mammals and Man [in Russian], vol. 11, Basel (1969).Google Scholar
  11. 11.
    R. J. Levin, H. Newey, and D. H. Smyth, J. Physiol. (London),177, 58 (1965).Google Scholar
  12. 12.
    W. C. Watson, E. S. Murray and M. D. Gardener, J. Clin. Path.,20, 185 (1967).Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • K. Rakhimov
  • U. Z. Kadyrov
  • B. Zaripov

There are no affiliations available

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