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Energy metabolism in the rat brain in the course of traumatic shock

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The concentration of high-energy phosphates (ATP, creatine phosphate), the total content of adenyl nucleotides, and the energy potential of the brain cells did not change significantly in experimental animals after trauma to the soft tissues of the thigh, until the terminal phase. The intensity of glycolysis was increased. In the terminal phase anaerobic processes predominated somewhat over aerobic. The absence of changes in the concentration of high-energy phosphates in the rat brain in traumatic shock is probably associated with centralization of the circulation and it is evidence that no “critical” exhaustion of energy takes place in the brain.

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Authors
  1. G. D. Shushkov
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  2. É. E. Kovrizhnykh
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  3. R. I. Kuz'mina
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  4. V. I. Semkin
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  5. T. V. Kazueva
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Shushkov, G.D., Kovrizhnykh, É.E., Kuz'mina, R.I. et al. Energy metabolism in the rat brain in the course of traumatic shock. Bull Exp Biol Med 78, 1245–1247 (1974). https://doi.org/10.1007/BF00804346

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  • DOI: https://doi.org/10.1007/BF00804346

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