Bulletin of Experimental Biology and Medicine

, Volume 79, Issue 3, pp 315–317 | Cite as

Cytochemical investigation of dynamics of RNA synthesis demonstrated in metaphase chromosomes of HeLa cells

  • A. A. Kucheryavenko
Experimental Biology


The dynamics of synthesis of DNA and chromosomal RNA, demonstrated in metaphase chromosomes of HeLa cells, was investigated by methods of selective extraction of cells in mitosis from the monolayer and pulse labeling. The results showed that chromosomal RNA is itself synthesized chiefly at the end of the G1- and beginning of the S-period. The synthesis of chromosomal RNA was found in the G2-period or during mitosis.

Key Words

chromosomes RNA synthesis mitosis colchicine 


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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • A. A. Kucheryavenko

There are no affiliations available

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